Found 12 matching trials
A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma PHASE1 This is a multicenter, open-label, ascending-dose trial of the safety and t...
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A Study of Toca 511 & Toca FC in Patients With Recurrent High Grade Non-Muscle Invasive Bladder Cancer (Toca 8) PHASE1 This is a Phase 1, multicenter, open-label study of intravesical Toca 511 f...
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Multiple Locations
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The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma PHASE2 This is a multicenter, randomized, open-label phase 2/3 study of Toca 511 a...
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Barrow Neurological Institute at Dignity Health St. Joseph's Hospital and Medical Center
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A Study of the Safety of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Subjects With Newly Diagnosed High Grade Glioma Receiving Standard of Care PHASE1 This is a multi-center, open label trial of combination therapy with Toca 5...
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Multiple Locations
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A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511 PHASE1 This is a multicenter, open-label, continuation study to allow subjects who...
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University of California, Los Angeles
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DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma PHASE2 The purpose of this study is to determine if the investigational products, ...
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University of Miami Hospital
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Clinical Study on the Safety and Efficacy of Novel Oncolytic Virus in the Treatment of Recurrent Malignant Glioma PHASE1 Glioma is the most common intracranial tumor. Among them, malignant glioma ...
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Beijing Tiantan Hospital
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A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6) PHASE1 The purpose of this trial is to evaluate changes in immune activity relativ...
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Sarah Cannon Research Institute
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Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor PHASE1 This is a multicenter study evaluating the safety and tolerability of Toca ...
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DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma PHASE1 This is a multicenter, open-label study of DB107-RRV (formerly Toca 511) an...
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University of Southern California
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